Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Experimental details, analytical data, and characterization for reactions in Tables 1 and 2 (PDF). Z
The "beta-position" is the next one after the alpha position. Practical and robust method for stereoselective preparations of ketene silyl (thio)acetal derivatives and NaOH-catalyzed crossed-Claisen condensation between ketene silyl acetals and methyl esters. 3
Esters with α-hydrogen atom on treatment with a strong base, e.g. 5.11: Enolates - Claisen Condensation and Decarboxylation, [ "article:topic", "Claisen condensation", "Enolates", "authorname:cschaller", "showtoc:no", "license:ccbync", "Claisen Decarboxylation" ], 5.12: Condensation Polymers and Ring-Opening Trans-Esterification Polymerisation, College of Saint Benedict/Saint John's University, (College of Saint Benedict / Saint John's University). Akira Iida,, Hiroki Okazaki,, Tomonori Misaki,, Makoto Sunagawa,, Akira Sasaki, and. Tapas R. Pradhan, Kishor L. Mendhekar, and Debendra K. Mohapatra . Guoqiang Zhou, Daniel Lim and Don M. Coltart. VIEWS . Yusuke Hisanaga, Yuya Asumi, Masaki Takahashi, Yasuhiro Shimizu, Nobuyuki Mase, Hidemi Yoda, Kunihiko Takabe. Information. A double Mannich approach to the synthesis of substituted piperidones—application to the synthesis of substituted E-ring analogues of methyllycaconitine. First, the ester portion of the molecule is converted into a carboxylic acid. the Altmetric Attention Score and how the score is calculated. Nature of Carbonyl Group. Pentafluorophenylammonium Trifluoromethanesulfonimide: Mild, Powerful, and Robust Catalyst for Mukaiyama Aldol and Mannich Reactions between Ketene Silyl Acetals and Ketones or Oxime Ethers. These esters will be electrophiles. An α-hydrogen in an ester is weakly acidic than the α-hydrogen of aldehydes or ketones, because the carbonyl group helps accommodate the negative charge of the carbanion to a lesser extent. These ions will be nucleophiles. Qinggang Wang, Manuel van Gemmeren, Benjamin List. Yuki Ban, Yuichiro Ashida, Hidefumi Nakatsuji, Yoo Tanabe. The formation of a beta-ketoester from two esters is called a "Claisen condensation". Yuichiro Ashida, Satomi Kajimoto, Hidefumi Nakatsuji, Yoo Tanabe. These metrics are regularly updated to reflect usage leading up to the last few days. It is one of the important name reactions of class 12 chemistry. IV
An α-hydrogen in an ester is weakly acidic than the α-hydrogen of aldehydes or ketones, because the carbonyl group helps accommodate the negative charge of the carbanion to a lesser extent. Asymmetric Disulfonimide-Catalyzed Synthesis of δ-Amino-β-Ketoester Derivatives by Vinylogous Mukaiyama-Mannich Reactions. Metal-Free
Practical method for the synthesis of (R)-homopipecolinic acid and (R)-homoproline esters from ω-chloroalkanoic acids and available chiral amines. You’ve supercharged your research process with ACS and Mendeley! It is often followed by another important reaction: decarboxylation. Hidefumi Nakatsuji, Hiroshi Nishikado, Kanako Ueno and Yoo Tanabe. Dahyeon Yang, Taeil Shin, Hyunwoo Kim, Sunwoo Lee. Recent Developments and Perspectives in the Zinc-Catalysed Michael Addition. Stereoretentive Iron‐catalyzed Cross‐coupling of an Enol Tosylate with
Fluorinated Musk Fragrances: The CF
Tomonori Misaki,, Satoko Ureshino,, Ryohei Nagase,, Yumiko Oguni, and. Synthesis of the seed germination stimulant 3-methyl-2H-furo[2,3-c]pyran-2-ones utilizing direct and regioselective Ti-crossed aldol addition. General, Robust, and Stereocomplementary Preparation of α,β-Disubstituted α,β-Unsaturated Esters. In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed. Benzoin condensation is due to stability of intermediate (III) when negative charge on C is extensively delocalised in benzene ring, Nitro and CN group. The classic Claisen condensation, a self-condensation between two molecules of a compound containing an enolizable ester. Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. A novel route to 4-oxy/thio substituted-1H-pyrazol-5(4H)-ones via efficient cross-Claisen condensation. The Claisen condensation is a carbon–carbon bond forming reaction that occurs between two esters or one ester and another carbonyl compound in the presence of a strong base, resulting in a β-keto ester or a β-diketone. Mikiko Sugi, Ryohei Nagase, Tomonori Misaki, Hidefumi Nakatsuji, Yoo Tanabe. The present method was extended to the condensation between a 1:1 mixture of carboxylic acids and carboxylic esters (six examples, ∼70−92% yield; cross/self-selectivity = ∼91/9−99/1).